Interactive mixed reality white cane simulation for the training of the blind and the visually impaired

This paper presents a mixed reality tool developed for the training of the visually impaired based on haptic and auditory feedback. The proposed approach focuses on the development of a highly interactive and extensible Haptic Mixed Reality training system that allows visually impaired to navigate into real size Virtual Reality environments. The system is based on the use of the CyberGrasp™ haptic device. An efficient collision detection algorithm based on superquadrics is also integrated into the system so as to allow real time collision detection in complex environments. A set of evaluation tests is designed in order to identify the importance of haptic, auditory and multimodal feedback and to compare the MR cane against the existing Virtual Reality cane simulation system.     

Prefetching in Content Distribution Networks via Web Communities Identification and Outsourcing

Content distribution networks (CDNs) improve scalability and reliability, by replicating content to the “edge” of the Internet. Apart from the pure networking issues of the CDNs relevant to the establishment of the infrastructure, some very crucial data management issues must be resolved to exploit the full potential of CDNs to reduce the “last mile” latencies. A very important issue is the selection of the content to be prefetched to the CDN servers. All the approaches developed so far, assume the existence of adequate content popularity statistics to drive the prefetch decisions. Such information though, is not always available, or it is extremely volatile, turning such methods problematic. To address this issue, we develop self-adaptive techniques to select the outsourced content in a CDN infrastructure, which requires no apriori knowledge of request statistics. We identify clusters of “correlated” Web pages in a site, called Web site communities, and make these communities the basic outsourcing unit. Through a detailed simulation environment, using both real and synthetic data, we show that the proposed techniques are very robust and effective in reducing the user-perceived latency, performing very close to an unfeasible, off-line policy, which has full knowledge of the content popularity.     

A Holistic Evolutionary and 3D Pharmacophore Modelling Study Provides Insights into the Metabolism,Function, and Substrate Selectivity of the Human Monocarboxylate Transporter 4 (hMCT4)

Monocarboxylate transporters (MCTs) are of great research interest for their role in cancer cell metabolism and their potential ability to transport pharmacologically relevant compounds across the membrane. Each member of the MCT family could potentially provide novel therapeutic approaches to various diseases. The major differences among MCTs are related to each of their specific metabolic roles, their relative substrate and inhibitor affinities, the regulation of their expression, their intracellular localization, and their tissue distribution. MCT4 is the main mediator for the efflux of L-lactate produced in the cell. Thus, MCT4 maintains the glycolytic phenotype of the cancer cell by supplying the molecular resources for tumor cell proliferation and promotes the acidification of the extracellular microenvironment from the co-transport of protons. A promising therapeutic strategy in anti-cancer drug design is the selective inhibition of MCT4 for the glycolytic suppression of solid tumors. A small number of studies indicate molecules for dual inhibition of MCT1 and MCT4; however, no selective inhibitor with high-affinity for MCT4 has been identified. In this study, we attempt to approach the structural characteristics of MCT4 through an in silico pipeline for molecular modelling and pharmacophore elucidation towards the identification of specific inhibitors as a novel anti-cancer strategy.     

Interfacial polymerization of pyrrole and in situ synthesis of polypyrrole/silver nanocomposites

We present a new synthetic approach leading to the formation of polypyrrole architectures in submicron level and to silver/polypyrrole nanocomposites via an interfacial polymerization in a water/chloroform interface. The oxidizing agent was either Ag(I) or Fe(III). In the first case, silver nanoparticles resulted. The mean diameter of the polypyrrole structures is in the range of 200-300 nm according to the addition or not of various surfactants. The progress of the reaction was studied by UV-visible spectroscopy, which also revealed the formation of a polaron band during the growth of the oligomers. The crystal structure of the polymers was examined by X ray diffractometry and all samples appeared to be amorphous, while the samples were further characterized by thermogravimetric analysis and FT-IR spectroscopy.     

The Neglected Water Rebound Effect of Income and Employment Growth

Water Resources Management - The water footprint assessment, particularly for the agricultural sector, is often a valuable input to water policy formation globally. Efforts on reducing it focus on...     

Cornet‐Like Phosphotriazine/Diamine Polymers as Reductant and Matrix for the Synthesis of Silver Nanocomposites with Antimicrobial Activity

The synthesis of silver nanoparticles attached on the surface of a hollow cornet‐like polymer matrix which served as a reductant and host matrix is described. This hybrid organic/inorganic macromolecular matrix is exhibiting anion‐exchange properties, porous structure and hollow morphologies, and absorptions in the visible light region. Due to the anion‐exchange property and the 3D orientation of the macromolecular chains the material is defining a new functional organic/inorganic hybrid. For the synthesis of nanoparticles, no other reducing agents were used and silver nanoparticles with a mean diameter of less than 20 nm were attached on the surface of the polymer, thus inheriting the composite with high antibacterial activity tested in bacterial strains and yeasts.

     

60 GHz indoor WLANs: insights into performance and power consumption

This paper presents a feasibility study of 60 GHz indoor WLANs. We evaluate 60 GHz performance in a typical academic office building under the primary assumption that 60 GHz WLAN APs and clients will be equipped with relatively wide-beam antennas to cope with client mobility. In contrast to previous works which measured performance at a single layer using custom, non-standard compliant hardware, we investigate performance across multiple layers using primarily 802.11ad-compliant wide-beam COTS devices. Our study shows that the large number of reflective surfaces in typical indoor WLAN environments combined with wider beams makes performance highly unpredictable and invalidates several assumptions that hold true in static, narrow-beam, Line-Of-Sight scenarios. Additionally, we present the first measurements, to our best knowledge, of power consumption of an 802.11ad NIC and examine the impact of a number of factors on power consumption.     

Enhancement of Bioactive Phenols and Quality Values of Olive Oil by Recycling Olive Mill Waste Water

Mature ‘Chondrolia Chalkidikis’ olives were processed in an industrial olive oil mill equipped with a three‐phase decanter. Water was added to the decanter at a 1:2 water‐to‐paste ratio. Olive mill waste water (ΟΜWW) was used to replace the added water at a rate of 50 or 100%. Following the final separation, the obtained oil was used for chemical analysis and sensory evaluation. All oils had similar acidity, peroxide and Κ values. OMWW‐treated olive oils presented higher total phenolic content and higher antioxidant activity based on DPPH and oven tests, but lower chlorophyll and carotenoids content. However, there was no significant difference between the 50 and 100% replacement. The phenolic profile of the treated olive oils analyzed by quantitative ¹Η NMR revealed more than twofold oleocanthal and oleacein as well as oleuropein and ligstroside aglycone contents than in the control. Sensory evaluation of treated oils also showed an enhancement of fruity, bitter and pungent attributes compared to the control.     

Rotordynamic Analysis of a Shaft Using Magnetorheological and Nanomagnetorheological Fluid Journal Bearings

The rotordynamic behavior of a system supported by journal bearings is critical to its reliability. A suitable method of control of the orbital motion of a shaft in a journal bearing is the use of smart lubricants, in effect fluids with controllable physical properties. There are various categories of smart lubricants. One class of smart lubricants, magnetorheological fluids, are produced as a dispersion of magnetic particles in a carrier fluid, which is usually a conventional lubricant. These particles form chains under the influence of a magnetic field, which hinder the lubricant flow, thus changing its apparent viscosity. Magnetorheological fluids (MRFs) exhibit high yield stress, low delay of response, and relatively low friction while not in their active state. A subcategory of MRFs, nanomagnetorheological fluids (NMRFs) with particle size on the nanometer scale, exhibits lower yield stress than MRFs but display high viscosity. The effect of the MRFs and NMRFs on the rotordynamic behavior of a shaft is calculated through a combined finite element and computational fluid dynamics analysis. Though the MRF with the specific geometrical configuration of the bearing is not sufficiently activated and therefore does not improve the performance of the magnetorheological journal bearing, the NMRF has the ability of limiting up to 82% the amplitude of the vibrations of the shaft.